VITAMIN D

Review Article: Vitamin D in dogs and cats and its relation to diseases not associated with bone metabolism.

Zafalon. 2020.

Vitamin D levels were lower in dogs with mast cell tumors compared to healthy dogs.

An increase in relative risk of splenic cancer was seen as vitamin D levels decreased in dogs.

Canine cancer patients may have altered vitamin D metabolism.

SHI QUAN DA BU TANG PREVENTS VINCRISTINE-INDUCED DIARRHEA IN DOGS

Efficacyof Juzen-taiho-to against vincristine-induced toxicity in dogs.

Shinohara. 2019.

Juzen-taiho-to increased gastric motility and improved vincristine-induced gastrointestinal, but not hematological, adverse effects in dogs. This study suggested that Juzen-taiho-to may be applicable for gastrointestinal care in dogs receiving chemotherapy.

CYTOKINES IN CANINE CANCERS 

Review Article: Cytokine Expression in Canine Lymphoma, Osteosarcoma, Mammary Gland Tumour and Melanoma: Comparative Aspects.

Irac. Vet Sci. 2019.

Cytokines in tumor microenvironment contribute to tumor growth, tumor progression, and regulation of the host anti-tumor response. As knowledge about the biological roles of cytokines in canine cancers increases and availability of biomarker testing in veterinary patients develops, better prognostication and therapy response assessment may improve the outcomes of canine patients with cancer.

SHI QUAN DA BU TANG ANTIOXIDANT ACTIVITY IN DOGS

Possible anti-oxidant effects of long-term administration of Juzen-taiho-to in dogs.

Shinohara. 2019

Long-term oral administration of Shi Quan Da Bu Tang reduced measures of oxidative stress in the blood of dogs. 

INFLAMMATORY RESPONSE AND OSA

Dogs with Osteosarcoma Have Altered Pro- and Anti-Inflammatory Cytokine Profiles.

Kikuchi. Am J Cancer Res. 2019.

Dogs with OSA have an altered cytokine production profile compared to healthy dogs that is not affected by the use of NSAIDs.

LIU JUN ZI TANG FOR NAUSEA IN DOGS

Intragastric Administration of Rikkunshito Stimulates Upper Gastrointestinal Motility and Gastric Emptying in Conscious Dogs

Yanai. 2013.

Liu Jun Zi Tang (rikkunshito) stimulated gastrointestinal contractions through cholinergic neurons and 5-HT type 3 receptors and increases ghrelin levels in plasma. It may alleviate gastrointestinal disorders through its prokinetic effects.

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